Supplementation of Thymoquinone and Carob Together in the Experimental Rat Asthma Model: Oxidative Effect on the Liver Tissue

Asthma, an important public health problem, is a common, potentially serious, medical condition in children, adults and pregnant women. The aim of this study to investigate the effects combined use thymoquinone carob on liver tissue oxidative events, following experimental asthma model. 18 male albino wistar rats were divided into 3 groups as: control group, group treated (A+TQ+C). In asthmatic groups, ovalbumin alum given intraperitoneally 0 14th days, sensitized by inhalation 21st, 22nd 23rd days. next 5 be intragastric gavage method. all glutathione (GSH), ascorbic acid (AA), malondialdehyde (MDA) nitric oxide (NOx) levels measured spectrophotometrically evaluate oxidant-antioxidant status rats. While GSH AA increased, NOx found decrease administration (A+TQ+C) when compared other (Control Asthma). However, MDA levels, which are indicator lipid peroxidation, statistically significantly increased (p